Mouse Cyclic AMP-dependent transcription factor ATF-1 (Atf1) ELISA Kit

The Assay Genie sandwich ELISA kit is designed for the accurate measurement of ATF1 levels in mouse samples, including serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. It targets mouse Cyclic AMP-dependent transcription factor ATF-1 (Atf1), also known as activating transcription factor 1 or TCR-ATF1, a nuclear transcription factor that binds the cAMP response element (CRE) and regulates gene expression downstream of cAMP and PKA signalling.

The colorimetric assay has a detection range of 15.6-1000 pg/mL and a sensitivity of 7.86 pg/mL. Specificity covers natural and recombinant mouse Cyclic AMP-dependent transcription factor ATF-1. Intended for research use only, the kit is suited to neurosciences research, supporting studies of ATF1 in processes such as cell growth, differentiation, proliferation and stress responses, and its reported involvement in cancer, inflammatory conditions and metabolic disorders.

Recommended storage is -20°C with shipping at +4°C. The target is annotated under UniProt P81269, and ATF1 binds DNA as a dimer, interacting with HIPK2 and CDK3.