Mouse Corticosteroid 11-beta-dehydrogenase isozyme 1 (Hsd11b1) ELISA Kit

A sandwich ELISA kit from Assay Genie is designed for the quantitative detection of mouse Corticosteroid 11-beta-dehydrogenase isozyme 1 (Hsd11b1). The kit uses a colorimetric ELISA detection method and is reactive with mouse samples, including serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Specificity is directed against natural and recombinant mouse Hsd11b1.

The assay has a detection range of 0.312-20ng/mL and a sensitivity of 0.184ng/mL. Hsd11b1 is a homodimer that localises to the endoplasmic reticulum membrane as a single-pass type II membrane protein and catalyses the reversible conversion of cortisol to the inactive metabolite cortisone. The research area associated with this target is cardiovascular. The UniProt accession for the target protein is P50172 and the reported molecular weight is 32,364 Da.

Synonyms for the target include 11-beta-hydroxysteroid dehydrogenase 1, 11beta-HSD1A, 11-DH, and Hsd11. Intra-assay CV, inter-assay CV, linearity, and recovery data are provided with the kit. The kit is intended for research use only.