Mouse Complement 1q (C1q) ELISA Kit

Quantitative analysis of Complement 1q (C1q), the recognition subunit that initiates the classical complement cascade, is supported by this immunoassay from Assay Genie configured for mouse specimens. C1q plays a central role in antibody-driven complement activation, opsonization of pathogens, and clearance of apoptotic debris, making circulating C1q levels a useful biomarker of complement activity in murine disease models.

Researchers apply the kit in studies of systemic lupus erythematosus-like autoimmunity, glomerulonephritis, neurodegeneration, and transplant rejection, as well as basic characterization of complement deficiency in knockout mouse strains.

Each kit arrives as a complete reagent set with pre-coated plate, recombinant C1q standards, detection antibody, and substrate, supporting up to 96 determinations per run. The plate-based ELISA protocol follows an incubation and wash workflow with substrate conversion and absorbance measurement at an appropriate wavelength. Validation work covers reproducibility and recovery to ensure consistent quantitation across experimental cohorts. Provided for research use only.