Mouse Complement 1 Inhibitor (C1INH) ELISA Kit

This quantitative immunoassay from Assay Genie enables measurement of Complement 1 Inhibitor (C1INH) in mouse specimens, supporting research into complement pathway regulation and related inflammatory models.

C1INH acts as the principal endogenous inhibitor of the classical complement cascade, restraining C1r and C1s proteases while also contributing to control of contact-system activation. Mouse models of hereditary angioedema, vasculitis, and ischemia-reperfusion injury commonly rely on circulating C1INH quantification to evaluate pathway activity, intervention timing, and treatment effects. The kit supplies pre-coated plates, detection antibody, calibrators, and substrate reagents for plate-based analysis.

Provided as a complete laboratory kit with components sufficient for 96 individual determinations, the assay employs a chromogenic endpoint readable on standard microplate instrumentation. Reagents should be kept refrigerated between uses and shielded from light to preserve activity. Each lot is calibrated against murine reference material, supporting reproducible inter-run quantification for longitudinal studies of complement dysregulation.