Mouse Collagen alpha-1 (XVIII)chain (Col18a1) ELISA Kit

This Sandwich ELISA Kit from Assay Genie is designed for the quantitative measurement of Collagen alpha-1 (XVIII) chain (Col18a1) in mouse samples. The assay is reactive with mouse serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and recognises natural and recombinant mouse Collagen alpha-1 (XVIII) chain.

Using a colourimetric detection method, the kit has a detection range of 0.156–10 ng/mL and a sensitivity of 0.09 ng/mL. Intra-assay CV, inter-assay CV, linearity and recovery data are provided with the kit. Sample preparation protocols cover serum, plasma, urine, cerebrospinal fluid, cell culture supernatant, cell lysates and tissue homogenates. Intended for research use only.

Endostatin, derived from COL18A1, potently inhibits endothelial cell proliferation and angiogenesis and may act by binding to heparan sulfate proteoglycans involved in growth factor signalling. COL18A1 is a critical component of the extracellular matrix contributing to cell adhesion, migration and tissue development, with aberrant expression linked to cancer, fibrosis and vascular disorders, making the kit useful within Signal Transduction research.