Mouse CNR1  (Cannabinoid Receptor 1, Brain) ELISA Kit  (MOES01790)

Cannabinoid receptor type 1 (CB1) is the most abundant G-protein coupled receptor in the central nervous system, with dense expression throughout the hippocampus, cerebellum, basal ganglia, and cortex where it modulates GABAergic and glutamatergic neurotransmission, retrograde synaptic signaling, and neural plasticity. The Assay Genie Mouse CNR1 ELISA Kit delivers quantitative measurement of CB1 protein in mouse samples using an absorbance-based immunoassay on a standard microplate format.

This research-use-only kit supports neuroscience and pharmacology investigations, including studies of endocannabinoid tone, neuroinflammation, addictive behavior, appetite regulation, and responses of murine models to cannabinoid agonists and antagonists. Sample preparation may use serum-derived fractions, plasma fractions, or tissue lysates prepared from mouse brain regions. Each kit provides reagents sufficient for 96 determinations, including a pre-coated microplate, calibrated reference standards, detection antibody, substrate solution, and wash buffer.

The assay is calibrated specifically against the murine CB1 sequence and is intended for in vitro research applications. Store all components refrigerated and protect from light to preserve reagent activity. Researchers commonly integrate results with western blot, immunohistochemistry, or quantitative PCR to build a multi-modal picture of cannabinoid receptor expression across experimental mouse cohorts.