Mouse CDNF PharmaGenie ELISA Kit (SBRS1313)

For neuroscience and Parkinson's disease research, this immunoassay from Assay Genie quantitatively measures Cerebral Dopamine Neurotrophic Factor (CDNF) in mouse specimens. The kit targets the CDNF protein, a conserved neurotrophic factor characterized by an endoplasmic reticulum retention signal and studied for its capacity to protect and restore dopaminergic neurons in models of neurodegeneration, as well as its role in modulating the unfolded protein response. Researchers apply the assay to cell culture supernatants, as well as serum or plasma specimens collected from murine experimental systems, including studies of midbrain dopaminergic neuron survival, ER stress responses, and evaluations of CDNF as a candidate therapeutic for Parkinson's disease. The protocol uses a colorimetric readout measured on a standard microplate reader, with all reagents supplied for 96 determinations per plate. Each kit includes pre-coated wells, detection antibody, standards, and buffers required to generate a standard curve from which sample CDNF concentrations are interpolated. Reagents should be refrigerated upon arrival and equilibrated to room temperature before use. Intended for research use only, the kit supports workflows ranging from screening recombinant CDNF preparations and conditioned media to profiling endogenous circulating CDNF in transgenic and knockout mouse lines commonly used in Parkinson's and dopamine neuron research.