Mouse CD109 antigen (Cd109) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the precise measurement of mouse CD109 antigen (Cd109) levels in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. It uses a colorimetric detection method and is intended for research use only.

CD109 is a key protein involved in cell growth and differentiation, particularly in the regulation of TGF-beta signaling and inflammation. Dysregulation of CD109 expression has been linked to various diseases, including cancer and inflammatory disorders. The kit detects natural and recombinant mouse CD109 antigen with a quoted detection range of 0.312-20 ng/mL and a quoted sensitivity of 0.188 ng/mL.

The target is the GPI-anchored alpha-2 macroglobulin-related protein (CD109), a disulfide-linked heterodimer anchored to the cell membrane via a lipid GPI-anchor. It modulates negatively TGFB1 signaling in keratinocytes. The associated UniProt accession is Q8R422, with a molecular weight of 161,659 Da.