Mouse Caveolin 1 (CAV1) ELISA Kit

Caveolin-1 (CAV1) is the principal structural protein of caveolae, the flask-shaped plasma membrane invaginations that organize lipid rafts, regulate vesicular transport, and modulate signal transduction through pathways including MAPK and PI3K/Akt. The Mouse Caveolin 1 (CAV1) ELISA Kit from Assay Genie is a quantitative immunoassay designed to measure caveolin-1 concentrations in mouse-derived specimens, supporting research into the context-dependent roles of this protein in cancer biology, cardiovascular disease, and pulmonary fibrosis.

Configured as a 96-assay microplate for in vitro research use, the kit accommodates caveolin quantification in lung, cardiac, adipose, and neural tissue homogenates, alongside serum-type and plasma-type specimens collected from laboratory mice. Documented applications include cancer investigations of CAV1 as a tumor suppressor or metastatic facilitator, cardiovascular studies of caveolae-mediated mechanotransduction, and analyses of pulmonary hypertension and fibrosis models.

The assay supports comparative work between wild-type mice and CAV1 knockout or transgenic lines, enabling researchers to monitor genotype- and treatment-dependent shifts in caveolin abundance across tissues and sample types. Complementary downstream workflows such as western blot validation of fractionated membrane preparations, immunohistochemistry on tissues flagged by the ELISA readout, and flow cytometry confirmation of caveolar markers extend the utility of caveolin-1 measurements within a broader experimental pipeline.