Mouse Carboxypeptidase N subunit 2 (Cpn2) ELISA Kit

Designed for the quantitative measurement of Mouse Carboxypeptidase N subunit 2 (Cpn2), this Sandwich ELISA Kit from Assay Genie is suitable for use with mouse serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay uses a colorimetric detection method and shows specificity for natural and recombinant mouse CPN2. The product is intended for research use only.

CPN2 is a secreted protein (UniProt: Q9DBB9) that functions as the 83 kDa subunit, binding and stabilizing the catalytic subunit at 37 °C and keeping it in circulation. Under some circumstances, this subunit may also act as an allosteric modifier of the catalytic subunit. The native complex forms a tetramer of two catalytic chains and two glycosylated inactive chains. CPN2 plays a role in the regulation of inflammatory responses and blood coagulation, and its dysregulation has been associated with autoimmune diseases, inflammatory disorders, and coagulation disorders, supporting its relevance as a potential biomarker in related research.

According to the manufacturer's specifications, the kit offers a detection range of 1.56-100ng/mL and a sensitivity of 0.69ng/mL. Reagents are stored at -20 °C and the product is shipped at +4 °C. The associated research area is Signal Transduction.