Mouse Calpain-2 catalytic subunit (Capn2) ELISA Kit

From Assay Genie, this Sandwich ELISA kit is intended for the detection and quantification of the mouse Calpain-2 catalytic subunit (Capn2). It uses a colorimetric detection method and is reactive with mouse samples, including serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. The kit shows specificity for natural and recombinant mouse Calpain-2 catalytic subunit.

According to the manufacturer's specification, the assay has a detection range of 0.312–20 ng/mL and a sensitivity of 0.156 ng/mL. The captured target is also known by several synonyms, including 80 kDa M-calpain subunit, Calcium-activated neutral proteinase 2, Calpain M-type, Calpain-2 large subunit, Millimolar-calpain, CALP80, CANP 2 and M-calpain, and the associated UniProt identifier is O08529.

Capn2 is described as a calcium-regulated non-lysosomal thiol-protease involved in cytoskeletal remodelling and signal transduction. Its dysregulation has been implicated in muscular dystrophy, neurodegenerative disorders and cancer, making the kit a useful tool for research in the neurosciences area. The product is supplied for research use only.