Mouse Calcitonin gene-related peptide 2 (Calcb) ELISA Kit

Designed by Assay Genie, the Mouse Calcitonin gene-related peptide 2 (Calcb) ELISA Kit is a sandwich-format immunoassay for the quantitative detection of CALC (Calcitonin Gene-Related Peptide 2) in mouse serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. It uses a colorimetric readout and is reactive with mouse samples, supporting research into pain modulation and inflammation regulation. CALC, also referred to as Beta-type CGRP, Calcitonin gene-related peptide II, or CGRP-II, has been implicated in various inflammatory conditions and serves as a biomarker for studying these processes.

Performance specifications include a detection range of 15.6-1000pg/mL and a sensitivity of 7.94pg/mL, with reported intra-assay CV of 7.3% and inter-assay CV of 9.0%. Recovery values for serum average 96% (range 90-102%) and for plasma average 98% (range 92-104%). The kit shows specificity for natural and recombinant mouse Calcitonin gene-related peptide 2, a secreted protein with a molecular weight of 14,623 Da (UniProt: Q99MP3).

CGRP is known to induce vasodilation, acting on the coronary, cerebral, and systemic vasculature, and its abundance in the central nervous system suggests a neurotransmitter or neuromodulator role. For research use only.