Mouse Cadherin-1 (Cdh1) ELISA Kit

From Assay Genie, this sandwich ELISA kit is intended for the quantitative measurement of Mouse Cadherin-1 (Cdh1), a calcium-dependent cell adhesion molecule also referred to as ARC-1, Epithelial cadherin, Uvomorulin, E-cadherin, or CD324. The kit is reactive with mouse samples and is validated for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, with specificity for both natural and recombinant mouse Cadherin-1.

According to the manufacturer's specifications, the kit has a detection range of 78-5000pg/mL and a sensitivity of 39.1pg/mL. Reported precision is 8.7% intra-assay CV and 10.5% inter-assay CV. Linearity has been assessed in serum, EDTA plasma, and heparin plasma across serial dilutions from 1:2 to 1:16, with average recovery of 90% for serum (range 84-96%) and 92% for plasma (range 86-98%). The target is associated with the research area Cancer, and storage is at -20°C. The kit is for research use only.

Cadherin-1 is described as a single-pass type I membrane protein that functions as a disulfide-linked homodimer and forms part of an E-cadherin/catenin adhesion complex. UniProt entry P09803 notes that defects in CDH1 are implicated in dysfunction of the cell-cell adhesion system and in cancer invasion and metastasis. Independent suppliers including Hölzel Diagnostika and Biomol also list the product.