Mouse C-C motif chemokine 7 (Ccl7) ELISA Kit

This Sandwich ELISA kit from Assay Genie is designed for the quantification of C-C motif chemokine 7 (Ccl7), also known as Monocyte Chemoattractant Protein-3 (MCP-3), in mouse samples. CCL7 is a key chemokine involved in the recruitment and activation of monocytes, T cells, and other immune cells, playing a role in inflammatory responses, immune cell migration, and the regulation of immune cell function. Measurement of CCL7 levels supports research in immunology, inflammation, and related fields.

Validated sample types include serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The kit is specific for natural and recombinant mouse C-C motif chemokine 7. Reported performance characteristics include a detection range of 15.6-1000pg/mL, a sensitivity of 7.84pg/mL, an intra-assay CV of 6.3%, and an inter-assay CV of 7.5%. Linearity in serum (N=5) spans 103-116% at 1:2, 93-105% at 1:4, 95-103% at 1:8, and 103-112% at 1:16 dilution, with comparable ranges reported for EDTA plasma and heparin plasma. Recovery averages 100% (94-106%) in serum and 102% (96-108%) in plasma. The UniProt entry for the target protein is Q03366 (gene symbol Ccl7), and CCL7 is described as a secreted monomer that acts as a chemotactic factor for monocytes and eosinophils but not neutrophils, also augmenting monocyte anti-tumor activity. For research use only.