Mouse BMP2 ELISA Kit

From Assay Genie, this Mouse BMP2 ELISA Kit is a sandwich ELISA, double antibody assay designed for the precise measurement of Bone Morphogenetic Protein 2 (BMP2) levels. BMP2 is a critical growth factor that plays a key role in bone formation and regeneration, and is also involved in embryonic development and tissue repair. Dysregulation of BMP2 has been linked to skeletal disorders, cardiovascular diseases, and certain cancers, making it a relevant biomarker for research in these areas.

The kit shows a sensitivity of 37.5 pg/mL and a range of 62.5-4000 pg/mL, with reactivity against mouse samples including serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. Detection is colorimetric, with absorbance read at 450 nm. The workflow uses a biotin-labeled detection antibody and HRP-Streptavidin (SABC), with TMB substrate for color development.

Validated performance includes linearity of 88-101% for serum, 85-104% for EDTA plasma, and 89-104% for heparin plasma at the 1:2 dilution (n=5), and recovery ranges of 93-101% for serum, 85-102% for EDTA plasma, and 89-101% for heparin plasma. The kit is stored at 2-8°C for 12 months. The product has been cited in published research, including a 2023 Biomolecules study by Wytrwal et al. (PubMed ID: 37238712) on cellular responses to BMP-2 and BMP-7.