Mouse BMG/ beta2-MG (Beta-2-Microglobulin) ELISA Kit (MOES01692)

Assay Genie supplies a colorimetric sandwich ELISA for measuring mouse BMG/β2-MG (beta-2-microglobulin) in biological samples. The kit reacts with mouse BMG/β2-MG and is intended for serum, plasma and other biological fluids, using a sample volume of 100 μL. Reported sensitivity is 0.19 ng/mL across a detection range of 0.31-20 ng/mL, with recovery of 80%-120% and an assay time of 3 h 30 min.

Supplied components include a dismountable microplate, reference standard, concentrated biotinylated detection antibody, concentrated HRP conjugate, reference standard and sample diluent, biotinylated detection antibody diluent, HRP conjugate diluent, concentrated wash buffer, substrate reagent, stop solution and plate sealer, together with a technical manual and certificate of analysis. Storage is 2-8°C.

The manufacturer reports that the kit shows no significant cross-reactivity or interference between mouse BMG/β2-MG and analogues, and describes it as a reliable and accurate tool for measuring beta-2-microglobulin levels in mouse serum, plasma and cell culture supernatants. Beta-2-microglobulin is a key component of the major histocompatibility complex (MHC) class I molecules involved in immune response regulation, and changes in its levels have been linked to kidney disease, immune disorders and certain types of cancer. Research areas listed for the kit are cancer, cardiovascular and immunology.