Mouse BH3-interacting domain death agonist (Bid) ELISA Kit

Assay Genie provides a sandwich ELISA kit designed for the quantitative detection of mouse BH3-interacting domain death agonist (Bid) in biological samples. Bid is a pro-apoptotic member of the Bcl-2 superfamily that contains a BH3 death domain and plays a central role in cell death pathways by inducing caspases and apoptosis while counteracting the protective effect of Bcl-2. Dysregulation of Bid has been implicated in diseases such as cancer and neurodegenerative disorders, positioning it as a relevant target in neuroscience research and a potential biomarker for disease progression.

The assay is a sandwich ELISA with colorimetric detection and reactivity specific to mouse samples, including serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. It detects both natural and recombinant mouse BH3-interacting domain death agonist, with a detection range of 0.78-50ng/mL and a sensitivity of 0.443ng/mL. For research use only, the kit supports studies of apoptosis regulation, cytochrome c release, and mitochondrial involvement in cell death pathways. The associated UniProt entry is P70444.