Mouse Beta-hexosaminidase subunit alpha (Hexa) ELISA Kit

This Sandwich ELISA Kit, developed by Assay Genie, is designed for the quantitative determination of mouse Beta-hexosaminidase subunit alpha (HEXA). The assay employs a colorimetric readout and is intended for research use only. Listed synonyms for the target include Beta-N-acetylhexosaminidase subunit alpha, N-acetyl-beta-glucosaminidase subunit alpha, and Hexosaminidase subunit A.

The kit is reactive with mouse samples and has been validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. It specifically detects natural and recombinant mouse Beta-hexosaminidase subunit alpha. Quoted performance figures are a detection range of 15.6-1000pg/mL and a sensitivity of 7.8pg/mL; intra-assay CV, inter-assay CV, linearity and recovery data are provided with the kit.

HEXA is a lysosomal enzyme that degrades GM2 gangliosides and a variety of other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. The associated UniProt accession is P29416 and the subcellular localisation is the lysosome, placing the product within the Neurosciences research area and making it relevant to studies of lysosomal storage disorders such as Tay-Sachs disease.