Mouse Beta-defensin 1 (Defb1) ELISA Kit

Designed for the precise quantitative measurement of beta-defensin 1 in mouse samples, this Sandwich ELISA kit from Assay Genie offers a sensitive and specific tool for immunology and inflammation research. Beta-defensin 1 is a key antimicrobial peptide of the innate immune system, playing a role in host defense against pathogens, and its dysregulation has been linked to various inflammatory diseases and infectious conditions. The kit is validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and detects natural and recombinant mouse beta-defensin 1 (UniProt P56386), a secreted protein with a molecular weight of 7,749 Da.

Quantitative performance is reported with a detection range of 78-5000pg/mL and a sensitivity of 40.1pg/mL. Precision is characterised by an intra-assay CV of 5.7% and an inter-assay CV of 8.5%. Dilutional linearity has been established in serum, EDTA plasma and heparin plasma across 1:2 to 1:16 dilutions, with average recovery of 94% (88-100%) in serum and 96% (90-102%) in plasma. The targeted analyte exhibits bactericidal activity and may act as a ligand for the C-C chemokine receptor CCR6. For research use only.