Mouse Bcl-2-binding component 3 (Bbc3) ELISA Kit

From Assay Genie, this Mouse Bcl-2-binding component 3 (Bbc3) ELISA Kit is a sandwich ELISA intended for the detection of Bbc3 in mouse serum and plasma samples, using a colorimetric detection method.

Bbc3, also known as PUMA (p53 up-regulated modulator of apoptosis), is a member of the BCL-2 protein family that belongs to the BH3-only pro-apoptotic subclass. It functions as an essential mediator of p53-dependent and p53-independent apoptosis, interacting with anti-apoptotic BCL-2 family members and localising to the mitochondria to help regulate programmed cell death. Dysregulation of BBC3 has been implicated in numerous diseases, including cancer, autoimmune disorders, and neurological conditions, making it a relevant biomarker and research target.

The kit is supplied for research use only.