Mouse Bactericidal/Permeability Increasing Protein (BPI) ELISA Kit

Bactericidal/Permeability-Increasing Protein is a ~55 kDa cationic antimicrobial polypeptide stored in neutrophil azurophilic granules, where it binds the lipid A region of lipopolysaccharide and disrupts bacterial outer membranes. Quantitative measurement of circulating BPI supports research into sepsis, endotoxemia, Gram-negative bacteremia, and chronic inflammatory disease. The microplate is pre-coated with a mouse-reactive capture antibody and supplied with a biotinylated detection reagent and streptavidin-HRP. Reconstituted standards should be aliquoted and stored frozen to limit freeze-thaw degradation, and the unopened pouch should be refrigerated until first use. Assay Genie provides a complete protocol insert with each kit for straightforward assay setup.