Mouse ATP-binding cassette sub-family G member 2 (Abcg2) ELISA Kit

For quantitative measurement of mouse ATP-binding cassette sub-family G member 2 (Abcg2), Assay Genie offers a competitive ELISA kit validated for use with serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. The assay is reactive with mouse samples and shows specificity for natural and recombinant mouse Abcg2. Synonyms for the target include breast cancer resistance protein 1 homolog, urate exporter, and CD338.

Reported performance characteristics include a detection range of 0.312-20 ng/ml and a sensitivity of 0.165 ng/ml. Intra-assay CV is 7.6% and inter-assay CV is 10.1%. Recovery in serum averages 85% (range 80-91%) and in plasma 87% (range 81-93%).

Abcg2 functions as a high-capacity urate exporter with roles in porphyrin homeostasis and acting as a xenobiotic transporter. Its expression has been linked to cancer, cardiovascular disorders and neurological conditions. The associated UniProt accession is Q7TMS5. For research use only.