Mouse Asprosin (Asprosin) ELISA Kit (MOFI01465)

Built for the quantitative measurement of asprosin in mouse samples, this colorimetric ELISA from Assay Genie supports research into metabolic disorders such as type 2 diabetes, obesity, and polycystic ovary syndrome. Asprosin is a 140-amino-acid peptide hormone generated by the C-terminal cleavage of profibrillin (FBN1) in white adipose tissue, and it circulates in the bloodstream where it stimulates hepatic glucose release and acts on hypothalamic AgRP neurons to drive appetite. Mouse models are central to asprosin research because rodents recapitulate the fasting-induced rise in circulating asprosin and the corresponding effects on hepatic gluconeogenesis and food intake.

The kit provides microplate-based reagents calibrated for use with mouse serum or plasma specimens, enabling investigators to profile circulating asprosin in wild-type, knockout, and diet-induced disease models. Each kit includes a microwell plate, standards, detection antibody, and assay buffer sufficient to run a full plate of samples alongside standard curves. Researchers can apply the assay to longitudinal study designs, including time-course sampling during fasting-refeeding experiments, to track dynamic changes in asprosin secretion in response to a metabolic challenge.

Workflow involves standard incubation and wash steps read on a conventional microplate reader, making it compatible with most laboratory infrastructure. The kit is intended for research use only and fits academic labs, pharmaceutical discovery programs, and translational endocrinology studies focused on adipose-derived hormone signaling.