Mouse Aquaporin 2, Collecting Duct (AQP2) ELISA Kit

Aquaporin-2 (AQP2) is a vasopressin-regulated water channel concentrated at the apical membrane of renal collecting duct principal cells, where it mediates water reabsorption and supports urinary concentration. This mouse-specific immunoassay from Assay Genie is configured to measure AQP2 protein levels in tissue homogenates and cell lysates, providing a quantitative tool for research into nephrogenic diabetes insipidus, vasopressin signaling, and collecting duct water-handling physiology.

The kit includes reagents sufficient for 96 assays in a microplate format and is intended for in vitro research use only. Researchers studying renal aquaporin regulation, hydronephrosis, lithium-induced nephrogenic diabetes insipidus, or polyuria syndromes can apply this assay to track changes in AQP2 abundance across experimental conditions such as hydration challenge, genetic knockout, or pharmacological treatment. Sample preparation typically involves homogenizing kidney tissue or cultured collecting duct cells in lysis buffer, with samples stored refrigerated until analysis.