Mouse Aquaporin-2 (Aqp2) ELISA Kit

From Assay Genie, this Mouse Aquaporin-2 (AQP2) ELISA Kit is designed for the accurate quantification of AQP2 levels in mouse samples. The kit is validated for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, and shows specificity for natural and recombinant mouse Aquaporin-2.

The assay delivers a detection range of 0.625-40ng/mL with a sensitivity of 0.323ng/mL. Reported precision values are an intra-assay CV of 6.4% and an inter-assay CV of 8.0%. Linearity has been demonstrated across serum, EDTA plasma, and heparin plasma at dilutions of 1:2, 1:4, 1:8, and 1:16, with average recovery of 106% for serum (range 100-112%) and 108% for plasma (range 102-114%).

Aquaporin-2 is a water-specific channel protein that provides high water permeability to the plasma membranes of the renal collecting duct and plays an essential role in renal water homeostasis. The protein functions as a homotetramer and is shuttled to the apical cell membrane in a vasopressin-regulated manner. The target is catalogued under UniProt P56402 (NCBI Gene ID 11827) with a molecular weight of 28,965 Da. For research use only.