Mouse Aquaporin-12 (Aqp12) ELISA Kit

This high-quality ELISA kit from Assay Genie enables precise measurement of mouse Aquaporin-12 (AQP12) levels, also referred to by the synonym AQP-12. It is reactive with mouse samples and validated for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, showing specificity for both natural and recombinant mouse Aquaporin-12.

The assay offers a detection range of 0.312-20 ng/ml with a sensitivity of 0.166 ng/mL. Precision is characterized by an intra-assay CV of 6.4% and an inter-assay CV of 8.0%. Linearity has been validated at dilutions of 1:2 through 1:16 across serum, EDTA plasma, and heparin plasma. Recovery ranges from 100-112% (average 106%) for serum and 102-114% (average 108%) for plasma.

Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. AQP12 is a multi-pass membrane protein belonging to the MIP/aquaporin (TC 1.A.8) family and AQP11/AQP12 subfamily. Dysregulation of AQP12 has been linked to various physiological disorders, including renal diseases, skin conditions, and metabolic imbalances, underscoring its importance as a research target. For research use only.