Mouse Apolipoprotein B (APOB) ELISA Kit

Cardiovascular and metabolic disease research in murine models often hinges on accurate quantification of atherogenic lipoprotein particles, with Apolipoprotein B serving as the principal structural protein of LDL, VLDL, IDL, and chylomicron particles. The Mouse Apolipoprotein B (APOB) ELISA Kit from Assay Genie provides quantitative in vitro measurement of circulating APOB, supporting studies where particle number rather than cholesterol content alone is the variable of interest.

Each kit supports 96 assays run on a standard microplate, accommodating longitudinal and group-housed study designs typical of mouse phenotyping experiments. The assay is widely applied in transgenic and knockout research, including Apoe−/− and Ldlr−/− background strains, as well as in pharmacological studies evaluating PCSK9 inhibitors, statins, and antisense oligonucleotides that suppress hepatic APOB expression. Investigators also use APOB measurement to characterize hepatic VLDL secretion rates, intestinal chylomicron output, and the metabolic consequences of gene editing on lipid handling.

Reagents ship refrigerated and the kit is configured for research use only, providing the consumables needed for laboratory investigation of murine lipoprotein biology. Results inform studies of dyslipidemia, atherosclerosis progression, non-alcoholic fatty liver disease, and cardiometabolic risk in mouse models of human disease.