Mouse ANGPTL3 PharmaGenie ELISA Kit (SBRS1280)

The ANGPTL3 target functions as a key regulator of lipid metabolism, predominantly expressed in hepatic tissue where it modulates lipoprotein lipase and endothelial lipase activity. This immunoassay from Assay Genie offers quantitative measurement of endogenous angiopoietin-like protein 3 in mouse biological specimens, including cell culture supernatants, plasma, and serum samples. It supports research into dyslipidemia, fatty liver disease, and cardiovascular pathophysiology, where this secreted factor has attracted considerable interest as a therapeutic target in metabolic disorder drug development.

A standard microplate-based protocol generates absorbance readings proportional to ANGPTL3 concentration, with recombinant calibrator standards supplied to construct a reference curve across the working range. Each kit ships with reagents sufficient to complete a full plate workflow, supporting routine laboratory throughput. Reagents are shipped refrigerated to preserve antibody-binding activity and should be stored refrigerated upon arrival.

The workflow integrates with standard benchtop plate readers using visible-wavelength absorbance detection, fitting existing laboratory routines with straightforward sample handling. The assay accommodates the small sample volumes typical of murine studies, enabling serial collection from individual animals across longitudinal metabolic or pharmacodynamic investigations. Researchers in atherosclerosis, hepatic steatosis, or triglyceride regulation will find this research-use-only kit valuable for in vitro and in vivo investigation of ANGPTL3 biology in preclinical mouse models.