Mouse Angiotensin I Converting Enzyme (ACE) ELISA Kit

The Mouse Angiotensin I Converting Enzyme (ACE) ELISA Kit from Assay Genie enables quantitative measurement of ACE in mouse-derived samples. ACE is a zinc metallopeptidase central to the renin-angiotensin system, where it converts angiotensin I into the vasoconstrictor angiotensin II. Tracking ACE expression supports research in hypertension, cardiovascular remodeling, diabetic nephropathy, pulmonary injury, and ACE2-mediated mechanisms investigated in murine models.

Compatible sample matrices for this research-use-only assay include tissue homogenates, cell lysates, and cell culture supernatants, in addition to standard blood-derived preparations. The kit ships in a single microplate format with reagents supplied in individual vials. Unopened components should be refrigerated at 4 °C and equilibrated to room temperature before each run. Common applications include in vivo studies of ACE inhibitor pharmacology, longitudinal monitoring of renin-angiotensin activity in transgenic mice, and in vitro characterization of endothelial and pulmonary cell lines. Researchers tracking disease progression or treatment response in cohorts of knockout or wild-type mice use this assay to obtain standardized, comparable ACE measurements across experiments.