Mouse Angiotensin-converting enzyme 2 (Ace2) ELISA Kit

A quantitative immunoassay from Assay Genie, this kit targets a key regulatory carboxypeptidase of the renin-angiotensin system in mouse biology. The protein of interest is a zinc-dependent ectoenzyme anchored in plasma membranes and shed into circulation, where it opposes angiotensin II signaling and serves as the entry receptor used by SARS-CoV-2 in murine infection models.

Applications span cardiovascular, renal, pulmonary, and metabolic research, with frequent use in studies of hypertension, diabetic nephropathy, acute lung injury, and viral entry mechanisms. The assay supports work on transgenic and knockout mouse cohorts, longitudinal blood sampling, and pharmacological modulation of the ACE2/Ang-(1-7)/Mas receptor axis.

Each kit is configured for 96 assays with a microplate format, individually packaged reagent vials, and storage at 4°C between uses to minimize freeze-thaw stress on the capture antibody. Room temperature incubation steps pair with a small microliter sample load to streamline daily workflows, and results integrate cleanly with follow-up western blot, immunohistochemistry, flow cytometry, and quantitative PCR confirmation across mouse tissues.