Mouse Amine Oxidase, Copper Containing 3 (AOC3) ELISA Kit

AOC3, widely known as vascular adhesion protein-1 (VAP-1), is a copper-dependent semicarbazide-sensitive amine oxidase anchored to the luminal surface of vascular endothelial cells, where it catalyzes oxidative deamination of primary amines and supports leukocyte rolling, firm adhesion, and transmigration during inflammatory responses. The Assay Genie mouse AOC3 ELISA Kit is designed for quantitative detection of this bifunctional enzyme-adhesion molecule in murine specimens, enabling investigations of vascular inflammation, leukocyte trafficking, atherosclerosis, diabetic vasculopathy, hepatic fibrosis, and tumor cell extravasation.

Compatible with serum and tissue homogenate matrices harvested from in vivo mouse studies, the kit supplies reagents sufficient for 96 individual reactions run on a standard microplate, providing a practical platform for biomarker profiling in preclinical research programs. Investigators studying endothelial activation, oxidative stress linked to amine oxidase activity, or therapeutic modulation of leukocyte recruitment can deploy the assay across experimental cohorts, with components intended for research use only in appropriately equipped laboratory settings.