Mouse Alpha-synuclein (Snca) ELISA Kit

This Assay Genie sandwich ELISA kit is designed for the precise quantification of alpha-synuclein (Snca) levels in mouse serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and is supplied for research use only.

Alpha-synuclein is a protein linked to neurodegenerative diseases such as Parkinson's disease, where it plays a critical role in the formation of Lewy bodies, the pathological hallmarks of these disorders. By measuring alpha-synuclein levels in mouse models, researchers can investigate disease progression and potential therapeutic targets within the neurosciences field.

The colorimetric detection method delivers a detection range of 7.8-500pg/mL and a sensitivity of 3.9pg/mL. Reported precision values are an intra-assay CV of 8.3% and an inter-assay CV of 10.0%. The kit is specific for natural and recombinant mouse alpha-synuclein, with the target protein showing a molecular weight of 14.4 kDa (140aa) as confirmed by MALDI-TOF. Reported subcellular locations include cytoplasm, cytosol, membrane, nucleus, cell junction, synapse and secreted fractions.