Mouse Alpha-Fodrin (SPTAN1) ELISA Kit

Alpha-fodrin, the alpha-II spectrin subunit encoded by the SPTAN1 gene, is a core component of the membrane-associated cytoskeleton and a well-characterized substrate of calpains and caspases during apoptosis. The Mouse Alpha-Fodrin (SPTAN1) ELISA Kit from Assay Genie delivers quantitative measurement of this protein in murine samples using a colorimetric readout on a standard microplate reader, supplied as a 96-assay kit with pre-coated plate, reference standards, and detection antibodies. For research use only.

Validated reactivity is restricted to mouse specimens. The assay accepts tissue homogenates, cell lysates, and cell culture supernatants, supporting research on cytoskeletal remodeling, programmed cell death, and the autoimmune contexts in which anti-alpha-fodrin antibodies have been investigated, including Sjögren's syndrome. Researchers working on neurodegeneration, epithelial injury, or salivary gland pathology in murine models can track alpha-fodrin levels alongside downstream markers to follow proteolytic events tied to calpain or caspase activation.

All reagents are provided in vials and bottles ready for the workflow; store components as directed on the insert and protect from light to preserve the chromogen. Refer to the supplied protocol for working dilutions and standard curve preparation specific to this assay.