Mouse Alpha-actinin-3 (Actn3) ELISA Kit

A colorimetric sandwich ELISA kit from Assay Genie for the quantitative measurement of mouse Alpha-actinin-3 (ACTN3) in serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Alpha-actinin-3 is a structural protein primarily expressed in skeletal muscle, where it functions as an F-actin cross-linking protein that anchors actin to a variety of intracellular structures. Variations in the ACTN3 gene have been linked to differences in athletic performance and muscle metabolism, making the target relevant to studies of muscle physiology and sports genetics.

According to the manufacturer's specifications, the assay has a detection range of 78-5000 pg/mL and a sensitivity of 41 pg/mL, with absorbance read at 450 nm. The kit is specific for natural and recombinant mouse Alpha-actinin-3 and is listed for the Cancer research area.

Alpha-actinin-3 is catalogued under UniProt accession O88990 with a molecular weight of 103,043 Da. The protein is a homodimer with an antiparallel arrangement, can form heterodimers with ACTN2, and is reported to interact with MYOZ1. Listed for research use only.