Mouse Alpha-actinin-1 (Actn1) ELISA Kit

Designed for the quantitative measurement of mouse alpha-actinin-1 levels, this sandwich ELISA from Assay Genie is suitable for a range of research applications. The kit targets alpha-actinin-1 (Actn1), a cytoskeletal protein of the spectrin superfamily that functions as an F-actin cross-linking protein, anchoring actin to a variety of intracellular structures. It plays a key role in cytoskeletal organisation and cell adhesion, contributing to cell shape, movement, muscle contraction and cell migration.

Alpha-actinin-1 is recognised as an important biomarker because its dysregulation has been associated with various diseases, including muscular dystrophy and cancer. The protein is also known by the synonyms Alpha-actinin cytoskeletal isoform, F-actin cross-linking protein, and Non-muscle alpha-actinin-1, and the listed research area is cancer.

Compatible sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The kit detects natural and recombinant mouse alpha-actinin-1 and is intended for research use only.