Mouse Aldosterone Synthase (ALDOS) ELISA Kit

CYP11B2, the cytochrome P450 enzyme that catalyzes the terminal step of aldosterone biosynthesis in the zona glomerulosa of the adrenal cortex, can be quantified in mouse specimens with the Assay Genie Mouse Aldosterone Synthase (ALDOS) ELISA Kit. In rodent models, ALDOS levels serve as a biomarker for mineralocorticoid pathway activity, with applications in cardiovascular research, hypertension studies, and investigations of primary hyperaldosteronism and adrenal cortex function.

Configured for endocrinology workflows, the kit accommodates multiple specimen types and is supplied in a 96-assay microplate format. Reconstituted reagents require refrigerated storage and protection from light to preserve activity across the kit's shelf life, and any remaining wells remain available for follow-up measurements within that window. The protocol provides step-by-step guidance for sample preparation, incubation periods, washing, and data calculation.