Mouse Aldolase A, Fructose Bisphosphate (ALDOA) ELISA Kit

This quantitative immunoassay from Assay Genie enables precise measurement of Aldolase A (ALDOA), a key glycolytic enzyme that catalyzes the reversible cleavage of fructose-1,6-bisphosphate into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. Researchers apply the assay to studies of muscle metabolism, glycolytic pathway regulation, and cancer biology, where altered ALDOA expression has been linked to tumor progression and metabolic reprogramming in hepatocellular carcinoma, lung adenocarcinoma, and other malignancies.

The kit accommodates mouse-derived liquid and tissue-derived preparations, enabling characterization of enzymatic activity changes in models of muscle injury, hypoxia, and metabolic disease. Aldolase A is also a clinically relevant biomarker; elevated circulating levels are associated with myopathies, hemolytic anemia, and certain cancers, making this kit useful for translational investigations bridging murine models and human disease. Laboratories focused on cell biology, biochemistry, and oncology rely on ALDOA quantitation to assess glycolytic flux, evaluate gene knockouts, and screen compounds that modulate cellular energy metabolism.

Reagents and a pre-coated microplate are included with each kit, along with a complete protocol documented for research use only applications.