Mouse ALCAM/CD166 PharmaGenie ELISA Kit (SBRS1276)

Built around the activated leukocyte cell adhesion molecule (ALCAM, also designated CD166), this quantitative immunoassay from Assay Genie is intended for research use in mouse model systems. ALCAM is a 105 kDa transmembrane glycoprotein of the immunoglobulin superfamily that mediates homophilic and heterophilic cell-cell contacts through CD6 binding, and it is widely tracked in studies of T-cell activation, hematopoiesis, angiogenesis, and the behavior of tumor-initiating populations across solid tumor models.

The kit is configured as a plate-based ELISA for measuring soluble ALCAM in mouse cell culture supernatants and plasma samples. Researchers studying melanoma, breast carcinoma, prostate cancer, and glioma lines have relied on CD166 readouts to characterize stem-like subpopulations and metastatic potential. Each kit provides reagents for the indicated runs, with a capture antibody pre-coated on strip wells, a biotinylated detection antibody, streptavidin-HRP conjugate, recombinant standards, and assay diluent supplied in individual vials.

Recommended applications include quantification of circulating ALCAM in experimental autoimmune encephalomyelitis, monitoring of leukocyte trafficking in inflammation models, and longitudinal tracking of tumor progression in syngeneic mouse systems. The assay is for research use only and is not intended for diagnostic procedures.