Mouse Alanine Aminotransferase (ALT) ELISA Kit

Enabling quantitative measurement of alanine aminotransferase in mouse-derived samples, the Assay Genie Mouse ALT ELISA Kit supports researchers investigating hepatocellular injury, hepatic function, and liver-related disease mechanisms in murine models. ALT, also known as SGPT, is a cytoplasmic liver enzyme released into circulation during hepatocyte damage, serving as a widely used biomarker in toxicology and pharmacology studies.

Common applications include drug-induced liver injury (DILI) screening, evaluation of non-alcoholic fatty liver disease (NAFLD) models, alcoholic hepatitis research, hepatic fibrosis characterization, and assessment of hepatoprotective interventions. The kit is also employed in studies of metabolic disorders, ischemia-reperfusion injury, and genetic mouse models of liver disease.

Validated sample types accommodate experimental workflows spanning in vivo animal studies and in vitro hepatocyte work, including tissue homogenates, cell lysates, and standard biofluid preparations. Detection relies on a quantitative immunoassay with absorbance readout on standard microplate readers. The assay is specific to mouse ALT, with reactivity limited to the mouse species.

Each kit contains reagents for 96 assays, supporting medium-throughput workflows in academic laboratories and preclinical drug development pipelines. The Assay Genie Mouse Alanine Aminotransferase ELISA Kit is for research use only and is not intended for diagnostic procedures.