Mouse ADP-ribosyl cyclase 1 (Cd38) ELISA Kit

Designed for the accurate quantification of mouse ADP-ribosyl cyclase 1 (CD38), this Sandwich ELISA Kit from Assay Genie is intended for research use only. The assay is reactive with mouse samples and has been validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Detection is carried out by ELISA with a reported detection range of 0.78-50ng/mL and a sensitivity of 0.393ng/mL.

CD38 is a type II transmembrane glycoprotein that synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former acting as a second messenger for glucose-induced insulin secretion, and also displays cADPr hydrolase activity. The kit shows specificity for natural and recombinant mouse ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, and is grouped under the Cancer research area. Synonyms for the target include 2'-phospho-ADP-ribosyl cyclase, Cyclic ADP-ribose hydrolase 1, I-19, NIM-R5 antigen, ADPRC 1, cADPr hydrolase 1, and CD38. The associated UniProt entry is P56528, and the subcellular location is described as a membrane single-pass type II membrane protein.