Mouse Adenosine receptor A1 (Adora1) ELISA Kit

A high-quality sandwich ELISA format from Assay Genie designed for the quantitative measurement of mouse adenosine receptor A1 (ADORA1). The kit supports research into a receptor for adenosine whose activity is mediated by G proteins that inhibit adenylyl cyclase. ADORA1 is involved in the regulation of physiological processes including neurotransmission, inflammation, and cardiovascular function, and its dysregulation has been linked to neurodegenerative diseases, inflammatory disorders, and cardiovascular disease, making it a valuable target for research and drug development.

Validated for mouse reactivity across sample types including serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, with specificity for natural and recombinant mouse adenosine receptor A1. Quoted performance specifications include a detection range of 78-5000pg/mL, a sensitivity of 39pg/mL, an intra-assay CV of 8.5%, and an inter-assay CV of 10.4%. Recovery is reported as 102% (range 96-108%) for serum and 104% (range 98-110%) for plasma. Linearity has been characterised across serum, EDTA plasma, and heparin plasma at dilutions of 1:2, 1:4, 1:8, and 1:16.

The target is a multi-pass membrane protein located at the cell membrane and is associated with UniProt entry Q60612 (NCBI Gene ID: 11539). For research use only.