Mouse Acetyl-CoA acetyltransferase, mitochondrial (Acat1) ELISA Kit

Designed for the accurate measurement of mitochondrial Acetyl-CoA acetyltransferase (Acat1) levels in mouse samples, this Sandwich ELISA Kit from Assay Genie is intended for research use only. Acat1, also known by the synonym Acetoacetyl-CoA thiolase, is a mitochondrial enzyme that plays a major role in ketone body metabolism and is involved in fatty acid metabolism and cholesterol biosynthesis. Dysregulation of its activity has been implicated in various metabolic disorders, making it a crucial target for studying metabolic pathways and developing therapeutics.

The kit operates with a detection range of 7.8-500pg/mL and a sensitivity of 4.18pg/mL. It is reactive with mouse samples and validated for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Specificity covers natural and recombinant mouse Acetyl-CoA acetyltransferase, mitochondrial. The assay is suited to cardiovascular research, and the native protein is reported as a homotetramer with a molecular weight of 44,816 Da (UniProt Q8QZT1; NCBI Gene ID 110446; NCBI Official Symbol Acat1).