Mouse 8-OHdG (8-Hydroxydeoxyguanosine) ELISA Kit (MOFI01408)

This competitive immunoassay from Assay Genie quantifies 8-hydroxydeoxyguanosine, a principal marker of oxidative DNA damage, in mouse-derived research samples.

Hydroxyl radical attack on guanine residues produces 8-OHdG, which is excised by base-excision repair and circulates systemically, making its measurement a standard readout in studies of carcinogenesis, neurodegeneration, cardiovascular pathology, and aging in murine systems.

The kit supports longitudinal monitoring of oxidative stress in cohorts exposed to environmental toxins, pharmacological interventions, or genetic modifications, enabling correlation of 8-OHdG accumulation with downstream pathological endpoints.

Reagents are supplied for 96 determinations in a microplate-based format intended for in vitro research use only, and the assay is read on a standard microplate reader.

Investigators focused on inflammatory pathways, mitochondrial dysfunction, or DNA repair mechanisms will find this tool useful for characterizing oxidative burden in mouse models of human disease.