Mouse 15-LO (Arachidonate 15-Lipoxygenase) ELISA Kit (MOES01637)

Quantitative measurement of arachidonate 15-lipoxygenase in mouse research samples is enabled by this ELISA Kit from Assay Genie, supplied in a 96 assay configuration with colorimetric readout on a standard microplate reader.

Arachidonate 15-lipoxygenase (15-LO) is a non-heme iron-containing dioxygenase that catalyzes the stereospecific peroxidation of polyunsaturated fatty acids, converting arachidonic acid to 15-hydroperoxyeicosatetraenoic acid (15-HPETE) and downstream lipid mediators including lipoxins and resolvins. The enzyme is implicated in eosinophil maturation, airway inflammation, atherosclerosis, and resolution-phase inflammation, making it a target of interest in murine models of asthma, chronic obstructive pulmonary disease, and metabolic inflammation. Knockout and overexpression studies in mice have established 15-LO as a regulator of lipid-metabolic and immune signaling pathways.

This complete ELISA pack of reagents ships with a pre-coated microplate and is intended for research use only, allowing laboratories to run a standard curve and quantify 15-LO levels across experimental cohorts. Recommended for studies investigating inflammatory and lipid-metabolic pathways in mouse specimens, the kit supports batch analysis and reproducible inter-group comparisons.