Human ZO2 (Tight junction protein ZO-2) ELISA Kit (HUFI04828)

Zonula occludens-2, abbreviated ZO-2 and alternatively known as tight junction protein 2 (TJP2), is a peripheral membrane scaffolding protein of the MAGUK family that organizes the claudin and occludin strands of epithelial and endothelial tight junctions and links them to the underlying actin cytoskeleton. This immunoassay kit from Assay Genie is configured for the specific quantification of human ZO-2 in samples collected for research on epithelial and endothelial barrier function. Investigators working on cholestatic liver disease, hepatocellular and colorectal cancer biology, intestinal barrier disruption in inflammatory bowel conditions, and blood-brain barrier permeability use ZO-2 measurements alongside ZO-1, claudin-1, and occludin to monitor paracellular sealing under inflammatory, infectious, or pharmacological challenge. The kit is supplied as a complete reagent set in a well plate format compatible with standard microplate workflows, allowing standards, unknowns, and quality controls to be processed in parallel on a single plate. Reagents should be brought to room temperature before opening, and the assay is designated for research use only, not for clinical diagnostic procedures.