Human ZDHHC15 ELISA Kit (HUFI05592)

The ZDHHC15 enzyme is a Golgi-localized palmitoyl acyltransferase that catalyzes S-palmitoylation of substrate proteins, a reversible lipid modification essential for membrane association, trafficking, and synaptic signaling. Mutations in the X-linked ZDHHC15 gene have been linked to non-syndromic intellectual disability and bipolar disorder, making quantitative measurement of ZDHHC15 protein levels valuable for studies of neuronal lipid metabolism and X-linked neurodevelopmental disorders. Researchers investigating protein palmitoylation dynamics, membrane-bound enzyme expression, or genotype-phenotype correlations in patient-derived samples can use this Assay Genie quantitative immunoassay to compare ZDHHC15 abundance across cohorts. Each kit is supplied as a single-use microplate configuration with biotinylated detection antibody, streptavidin-HRP conjugate, calibrated reference standard, and TMB substrate, accompanied by a protocol with a typical sample volume of 100 uL. Sufficient reagents are included for duplicate plate runs, and the components should be refrigerated upon receipt with all materials equilibrated to room temperature before initiating the assay.