Human YWHAE PharmaGenie ELISA Kit (SBRS1242)

The YWHAE gene encodes 14-3-3ε, a phosphoserine/phosphothreonine-binding adaptor protein mapped to chromosome 17p13.3. It participates in signalling cascades regulating cell cycle progression, apoptosis, and neuronal migration, and rearrangements at this locus are a focus of cancer cytogenetics and developmental neuroscience research.

This Assay Genie PharmaGenie kit offers a reproducible immunoassay to quantify endogenous 14-3-3ε across multiple human specimen matrices and conditioned media from cultured cells. The kit ships as a complete reagent set in a microplate format with pre-coated wells, buffers, standards, and detection antibody. Components should be refrigerated between uses and protected from light to preserve activity.

Typical research applications include workup of ETV6-YWHAE fusion-positive paediatric leukaemia, studies of lissencephaly-related developmental pathways, and investigations of neuroprotective signalling in Alzheimer's and Parkinson's disease models.