Human XPNPEP3 ELISA Kit (HUFI05628)

The Human XPNPEP3 ELISA Kit from Assay Genie enables quantitative measurement of X-Prolyl Aminopeptidase 3, a mitochondrial matrix metalloenzyme (EC 3.4.11.9) that selectively cleaves N-terminal residues from peptides bearing a penultimate proline. Mutations in XPNPEP3 are linked to nephronophthisis-like nephropathy and ciliopathies, and altered expression has been studied in renal and mitochondrial contexts, making the kit a useful tool for nephrology, ciliopathy biology, and mitochondrial proteostasis research.

Each kit is supplied as a complete 96 Assays pack with pre-coated microplate wells, dilution buffer, detection antibody, and recombinant standards for generating a calibration curve. All reagents are intended for in vitro research use only and should be stored refrigerated to preserve activity through the kit shelf life. Researchers can apply the assay to measure endogenous XPNPEP3 levels in human clinical specimens for studies of kidney function, primary cilia biology, and mitochondrial peptide processing.