Human WNT1-inducible-signaling pathway protein 2 (WISP2) ELISA Kit

From Assay Genie, this ELISA kit is designed for the quantitative detection of human WNT1-inducible-signaling pathway protein 2 (WISP2) in human samples. WISP2 is a secreted protein of the WNT1-inducible signaling pathway, contributing to cell proliferation, migration, and tissue regeneration. The kit is intended for research use only and supports studies of disease mechanisms and biomarker investigation, including research into cancer, fibrosis, and metabolic disorders where dysregulation of WISP2 has been reported.

Reported intra-assay precision is 6.1% CV and inter-assay precision is 8.4% CV. The kit is specific for natural and recombinant human WISP2 and is validated for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. In spiked recovery testing, serum samples averaged 103% (range 97–109%) and plasma samples averaged 105% (range 99–111%).

WISP2, also known as CCN family member 5 (CCN5), belongs to the connective tissue growth factor (CTGF) family and is catalogued under UniProt entry O76076. Functional descriptions indicate that the protein may play an important role in modulating bone turnover, promoting adhesion of osteoblast cells, and inhibiting the binding of fibrinogen to integrin receptors.