Human WNT1-inducible-signaling pathway protein 1 (WISP1) ELISA Kit

Designed for the accurate detection of WNT1-inducible-signaling pathway protein 1 (WISP1), this Sandwich ELISA Kit from Assay Genie enables researchers to quantify WISP1 levels in human serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids. Also referred to as CCN family member 4, Wnt-1-induced secreted protein, WISP-1, and CCN4, WISP1 is a key protein in the Wnt signaling pathway that contributes to cell proliferation, migration, and tissue repair. Its dysregulation has been linked to diseases such as cancer, fibrosis, and osteoarthritis, making it a valuable biomarker for understanding disease mechanisms.

The assay delivers a detection range of 31.2-2000pg/mL with a sensitivity of 11.7pg/mL. Precision is characterised by an intra-assay CV of 6.2% and an inter-assay CV of 9.2%. Linearity data are provided across serial dilutions (1:2 to 1:16) of serum, EDTA plasma, and heparin plasma, with recoveries averaging 91% for serum (range 85-97%) and 93% for plasma (range 87-99%). The kit is specific for natural and recombinant human WISP1, targets the secreted form of the protein, and is supplied for research use only within the cancer research area.